Winter term 2013/2014, Begin: Oct. 22.
Lectures: Tuesday 14:15-15:45, IMB Mainz, Ackermannweg 4, Seminar room 2nd floor
Tutorial: Wednesday 14:15-15:00, Institut für Physik, Staudingerweg 7, CIP pool 03.423
Lab: Block course March 10-12, three full days.
Lecturers: Dr. Udo Birk, Prof. Dr. Christoph Cremer
Teaching language will be English, unless otherwise specified.
In the tutorials, a general introduction to the concept of image processing will be given, based on the programming environment MATLAB. Students will be given exercises to model the physical processes discussed during the lectures, and to evaluate the potential of the corresponding imaging / illumination / detection techniques.
In the lectures to Basics of Biomedical Optics 1 (winter term 2013/2014), i.e. in the first half of this two semester course, the main optical concepts of imaging and general technical aspects for realization of optical imaging devices are in focus. After an introduction to the electromagnetic concepts of light and its interaction with tissue, we will discuss recent development in technical optics (e.g. light sources, detectors) making possible the huge progress that biomedical imaging has recently seen. Several conceptual models representing (and simplifying) the optical image formation process will be discussed. Reasons for limitations in image resolution will be given, and means to overcome the technical problems will be presented. Contrasting mechanisms of optical imaging will be discussed and first approaches to enhance the 3D resolution in microscopy. The course will be complemented by a brief historical outline.
In the labcourse, several examples of high- and super-resolution microscopes will be worked
with in hands-on experiments. These microscopes will be applied to image biological specimens from
ongoing research collaborations. Students will perform image analysis to reconstruct represenations of
the biological structures at hand.
The aim is to provide the students with access to state-of-the art far field optical microscopy setups, illustrating the enormous progress that far field optical microscopy has recently made.
Jogustine entry for this course at the University of Mainz
| Date | Content | Lecturer |
|---|---|---|
| 22.10. | General outline of the course A short history of optics (glass, lenses, microscopes, telescopes, ...) | UB |
| 29.10. | What is color, what is scattering? The electromagnetic spectrum and the statistical nature of light | UB |
| 05.11. | Classical optics, from ray optics to wave optics to beam optics, some quantum optics Gaussian beam propagation | UB |
| 12.11. | Fourier Optics | UB |
| 19.11. | EM Dipole: near field, far field near field imaging | UB |
| 26.11. | Lasers: Theory, conditions, and technical realization | UB |
| 03.12. | History 1: The Advent of Microscopy | CC |
| 10.12. | Detectors Optical Design | UB |
| 17.12. | Radiometry Interaction of light and tissue: effects of laser power, pulse parameters | UB |
| 24.12. | Winter break | |
| 31.12. | Winter break | |
| 07.01. | White light generation Fluorescence and other contrasting mechanisms | UB |
| 14.01. | Optical Imaging 1: Image formation and Point Spread Function | UB |
| 21.01. | Optical Imaging 2: Limitations in imaging Apodization, Vectorial Diffraction Theory | UB |
| 28.01. | Confocal Laser Scanning Microscopy | CC |
| 04.02. | Axial Imaging: Micro-Axial Tomography, Theta Microscopy | UB |